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Can generic drugs work differently? The medicine has the same route of administration (such as oral or topical). The inactive ingredients of the medicine are acceptable. Some differences, which must be shown to have no effect on how the medicine functions, are allowed between the generic and the brand-name version.
Does spironolactone increase estrogen? As a diuretic, spironolactone can increase urination and induce disturbances in fluid and electrolyte balance with increased potassium levels. Since spironolactone acts as a mild estrogenic drug, it may in some females who have anovulatory cycles, induce ovulation and possibly fertility.
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